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Malignant skin tumors of neural crest origin
Author(s) -
Wahlström Torsten,
Saxén Lauri
Publication year - 1976
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197611)38:5<2022::aid-cncr2820380526>3.0.co;2-z
Subject(s) - neural crest , medicine , crest , pathology , variegation (histology) , soft tissue , anatomy , biology , genetics , embryo , physics , quantum mechanics
In a series of 90,000 consecutive surgical biopsies, ten malignant skin tumors were found that revealed at least two of three tissue components known to be derivatives of the neural crest, namely melanotic cells, neuroid structures, and chondrified tissue. The material studied supports a hypothesis presented earlier, that in spite of their morphologic variegation, such tumors form an entity defined by their common origin, the neural crest.