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Cervical lymph node metastasis as the first manifestation of localized extramedullary plasmacytoma
Author(s) -
Fishkin Ben G.,
Spiegelberg Hans L.
Publication year - 1976
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197610)38:4<1641::aid-cncr2820380433>3.0.co;2-y
Subject(s) - medicine , plasmacytoma , lymph node , multiple myeloma , cervical lymph nodes , bence jones protein , lymph , pathology , epiglottis , bone marrow , radiology , metastasis , larynx , cancer , immunoglobulin light chain , surgery , antibody , immunology
Two patients who had cervical lymph node metastases as the first symptom of a localized soft tissue extramedullary plasmacytoma of the epiglottis and nasopharynx, respectively, are described. Classical multiple myeloma was excluded by bone marrow biopsies and x‐ray studies of the skeleton. In both patients, the primary tumor was diagnosed 2 years after excision of the cervical lymph node. One patient had a IgD, λ myeloma protein in the serum and excreted λ Bence‐Jones protein into the urine. No M‐component was found in the other patient. Both are living with a long survival of 8 and 4 years, respectively. The presence of a cervical lymph node plasmacytoma should suggest an upper respiratory tract or oropharynx plasmacytoma rather than a primary lymph node plasmacytoma.