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Thymoma and chronic myelogenous leukemia. A case report
Author(s) -
Knowles Daniel M.
Publication year - 1976
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197609)38:3<1414::aid-cncr2820380348>3.0.co;2-x
Subject(s) - thymoma , medicine , chronic myelogenous leukemia , thymic carcinoma , leukemia , malignancy , pathology , chronic lymphocytic leukemia
A case of epithelial thymoma occurring synchronously with Philadelphia chromosome‐positive chronic myelogenous leukemia and urinary bladder carcinoma in a 76‐year‐old man is described. Thymomas have been associated with numerous hematologic, collagen‐vascular and autoimmune disease states, as well as with an increased incidence of nonthymic malignancy. Human thymoma‐associated leukemia is, however, extremely unusual, despite the well‐documented role of the thymus in leukemogenesis in experimental animals. No previous literature reports of thymoma associated with chronic myelogeneous leukemia were found. A review of long‐term followup data of surviving thymoma patients is necessary to determine if an increased propensity to develop leukemia is present in patients with thymoma.