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Oral methoxsalen photochemotherapy of mycosis fungoides
Author(s) -
Gilchrest Barbara A.,
Parrish John A.,
Tanenbaum Lewis,
Haynes Harley A.,
Fitzpatrick Thomas B.
Publication year - 1976
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197608)38:2<683::aid-cncr2820380210>3.0.co;2-v
Subject(s) - mycosis fungoides , methoxsalen , medicine , dermatology , puva therapy , psoriasis , lymphoma
The cutaneous manifestations of mycosis fungoides have been successfully treated in nine patients for 16 to 28 months with oral methoxsalen and subsequent irradiation with longwave ultraviolet light. The efficacy of this therapy was confirmed in one patient, who showed complete clearing of generalized plaques after 1 month (12 treatments) except for a shielded control area which worsened during this period. Methoxsalen photochemotherapy may prove a valuable addition to therapies currently available for mycosis fungoides and may obviate some of the problems associated with conventional management of this disorder.