Premium
Morbidity and mortality among recipients of blood from preleukemic and prelymphomatous donors
Author(s) -
Greenwald Peter,
Woodard Elizabeth,
Nasca Philip C.,
Hempelmann Louis,
Dayton Paul,
Maksymowicz Gregory,
Blando Paul,
Hanrahan L. Robert,
Burnett William S.
Publication year - 1976
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197607)38:1<324::aid-cncr2820380147>3.0.co;2-q
Subject(s) - medicine , haematopoiesis , etiology , leukemia , lymphoma , lymphatic system , blood transfusion , immunology , intensive care medicine , stem cell , genetics , biology
The present investigation was designed to test the admittedly speculative hypothesis that a factor involved in the etiology of human lymphatic and hematopoietic neoplasms may be transmitted by blood transfusion prior to the clinical onset of illness in the donor. One hundred and five New York State residents, who received blood from donors who subsequently developed neoplasms of the lymphatic or hematopoietic tissues, were identified and followed for an average period of 7.05 years. No recipient was found to have developed a leukemia or lymphoma following receipt of blood from a preleukemic or prelymphomatous donor. The results of this study should be considered preliminary because the small size of the recipient group might mask even a large increase in risk among the recipients.