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“Endometrial” adenocarcinoma of the prostate. A distinctive tumor of probable prostatic duct origin
Author(s) -
Zaloudek Charles,
Williams James W.,
Kempson Richard L.
Publication year - 1976
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197605)37:5<2255::aid-cncr2820370515>3.0.co;2-e
Subject(s) - medicine , prostate , adenocarcinoma , acid phosphatase , pathology , carcinoma , ejaculatory duct , staining , endometrium , prostatic acid phosphatase , ultrastructure , biology , cancer , seminal vesicle , enzyme , biochemistry
A so‐called “endometrial” adenocarcinoma of the prostate has been studied by light and electron microscopy, and by histochemical techniques. The previously proposed utricular origin and estrogen dependence of such tumors is questioned. Strong acid phosphatase staining, and the ultrastructural demonstration of multivacuolated, lipid, and lysosome‐containing tumor cells, suggest a prostatic ductal origin for this type of carcinoma despite the histologic similarity to carcinoma of the endometrium.