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Glassy cell carcinoma of the cervix
Author(s) -
Littman Philip,
Clement Philip B.,
Henriksen Birgit,
Wang C. C.,
Robboy Stanley J.,
Taft Priscilla D.,
Ulfelder Howard,
Scully Robert E.
Publication year - 1976
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197605)37:5<2238::aid-cncr2820370513>3.0.co;2-d
Subject(s) - pathology , carcinoma , medicine , cervix , adenosquamous carcinoma , uterine cervix , clear cell carcinoma , basal cell , nucleolus , cancer , adenocarcinoma , nucleus , psychiatry
A clinicopathologic analysis of 13 cases of glassy cell carcinoma of the uterine cervix is presented. The glassy cell carcinoma is considered to be a poorly differentiated mixed adenosquamous carcinoma. Its histologic appearance is distinctive, being characterized by cells with a moderate amount of cytoplasm having a ground glass or finely granular appearance, a distinct cell wall that stains with eosin and PAS, and enlarged nuclei with prominent nucleoli. In the present study this tumor was associated with extrapelvic spread in 6/13 cases at diagnosis. Results were poor with either surgery and/or radiotherapy. Only four of 13 patients survived 5 years. The glassy cell carcinoma appears to be a distinct clinicopathologic entity which warrants a place in the classification of carcinoma of the cervix.