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Ameloblastic sarcoma. Pathogenesis and treatment with chemotherapy
Author(s) -
Goldstein Gerald,
Parker Francis P.,
Slaughter Hugh G. Fitz
Publication year - 1976
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197604)37:4<1673::aid-cncr2820370410>3.0.co;2-t
Subject(s) - medicine , chemotherapy , vincristine , sarcoma , oncology , melanoma , pathology , cancer research , cyclophosphamide
A recurrent tumor in a young male demonstrates the progression of an ameloblastic fibroma to an ameloblastic sarcoma. Chemotherapy with Actinomycin D, Vincristine, and Cytoxan produced a complete response without evidence of recurrence 4 years after initiation of chemotherapy. The patient developed an aggressive malignant melanoma 1 year after all chemotherapy was discontinued.