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Congenital anomalies in children with Wilms' Tumor. A new survey
Author(s) -
Pendergrass Thomas W.
Publication year - 1976
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197601)37:1<403::aid-cncr2820370152>3.0.co;2-h
Subject(s) - aniridia , hemihypertrophy , wilms' tumor , medicine , genitourinary system , pediatrics , wilms tumour , pathology , biochemistry , chemistry , gene
From 68 hospitals in the National Wilms' Tumor Study, records of 547 patients showed six patients with aniridia, 16 with hemihypertrophy, and 24 with genitourinary abnormalities. Multiple cases of Wilms' tumor occurred in three families. The results confirm high frequencies of aniridia and genitourinary anomalies in patients with Wilms' tumor, and show that concurrence with hemihypertrophy may be more often recognized or recorded now than it was ten years ago. The results demonstrate the desirability of developing checklists for other childhood neoplasms some of which have their own constellation of anomalies.