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Cytogenetic studies in sideroblastic anemia
Author(s) -
Jensen Mogens Krogh,
Mikkelsen Margareta
Publication year - 1976
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197601)37:1<271::aid-cncr2820370137>3.0.co;2-9
Subject(s) - sideroblastic anemia , bone marrow , medicine , cytogenetics , pathology , anemia , karyotype , chromosome , biology , genetics , gene
Cytogenetic studies were performed on bone marrow aspirates from seven patients with acquired sideroblastic anemia. In one male patient a 45, X cell line was present in each of three bone marrow aspirates. The remaining six patients had a normal chromosome complement. The abnormal stem line in the bone marrow may be unrelated to the hematologic disorder or may indicate a neoplastic process still latent. The cytogenetic literature on sideroblastic anemia is reviewed.