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Medullary carcinoma of the thyroid. Cellular immune response to tumor antigen in a heritable human cancer
Author(s) -
George Jack M.,
Williams Marjorie A.,
Almoney Robert,
Sizemore Glen
Publication year - 1975
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197511)36:5<1658::aid-cncr2820360519>3.0.co;2-0
Subject(s) - medicine , medullary cavity , immune system , cancer , antigen , thyroid cancer , medullary carcinoma , medullary thyroid cancer , thyroid carcinoma , carcinoma , pathology , cancer research , immunology , thyroid , oncology
We have found inhibition of mononuclear leukocyte migration in response to tumor antigen in a group of patients with medullary carcinoma of the thyroid, a cancer inherited as an autosomal dominant. This immune response was not present in a group of family members who do not have cancer.