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The effects of therapeutic radiation on colonic mucosa
Author(s) -
Weisbrot Irwin M.,
Liber Amour F.,
Gordon Benjamin S.
Publication year - 1975
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197509)36:3<931::aid-cncr2820360314>3.0.co;2-r
Subject(s) - crypt , lamina propria , medicine , pathology , eosinophilia , cytology , eosinophilic , mucous membrane , intestinal mucosa , epithelium
Low to moderate doses of therapeutic irradiation are capable of producing bizarre cytologic changes in the mucosal cells of colorectal crypts. This may be associated with eosinophilia of the lamina propria and with eosinophilic crypt abscesses. The bizarre cells generally line intact crypts and do not exhibit invasive behavior. The change subsides within 1–2 months at the dose levels studied (∼2000 rads).