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Combination chemotherapy in oat cell carcinoma of the lung
Author(s) -
Nixon Daniel W.,
Carey Robert W.,
Suit Herman D.,
Aisenberg Alan C.
Publication year - 1975
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197509)36:3<867::aid-cncr2820360307>3.0.co;2-1
Subject(s) - procarbazine , medicine , vincristine , prednisone , cyclophosphamide , chemotherapy , regimen , oncology , oat cell carcinoma , radiation therapy , carcinoma , lung , combination chemotherapy , small cell carcinoma , surgery , lomustine , respiratory disease
Twenty‐eight patients with oat cell carcinoma of the lung were treated with cyclophosphamide, vincristine, procarbazine, and prednisone with and without irradiation. Median survival was significantly increased in this treatment group (10 months) as compared to a retrospective radiation alone series (5 months). Intensive chemotherapy with this four‐drug regimen represents an initial step in effective management of this disorder.