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Treatment of acute leukemia during pregnancy
Author(s) -
Raich Peter C.,
Curet Luis B.
Publication year - 1975
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197509)36:3<861::aid-cncr2820360305>3.0.co;2-p
Subject(s) - medicine , cytarabine , pregnancy , leukemia , acute leukemia , myelocytic leukemia , obstetrics , pediatrics , oncology , genetics , biology
Cytarabine and thioguanine therapy for acute myelocytic leukemia, initiated during the 26th week of pregnancy, led to complete remission of the leukemia in a 22‐year‐old woman, and allowed for delivery of a normal infant at term. No chromosomal abnormalities were detected in the infant. Cytarabine and thioguanine in combination are effective agents in the treatment of acute leukemia in adults. Their use appears warranted in pregnant patients after the first trimester.