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Growth rate of pulmonary metastases in human sarcomas
Author(s) -
Band Pierre R.,
Kocandrle Charles
Publication year - 1975
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197508)36:2<471::aid-cncr2820360225>3.0.co;2-4
Subject(s) - medicine , doubling time , histology , sarcoma , primary tumor , radiology , pathology , metastasis , nuclear medicine , cancer , cell , biology , genetics
The growth rate of spherical pulmonary metastases was studied in 15 patients with osseous and soft tissue sarcoma. The median volume doubling time (Dt) was 25 days. The time from diagnosis of the primary tumor to occurrence of pulmonary metastases correlated directly with the length of Dt. No correlation between Dt and tumor histology was observed. The effect of therapy on the tumor growth curve was studied in 1 patient. The therapeutic implications derived from the quantitative evaluation of tumor growth rate are discussed.