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Pancreatic neoplasms in an animal model: Morphological, biological, and comparative studies
Author(s) -
Pour Parviz,
Mohr Ulrich,
Cardesa Antonio,
Althoff Jürgen,
Krüger Friedrich W.
Publication year - 1975
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197508)36:2<379::aid-cncr2820360213>3.0.co;2-r
Subject(s) - medicine , pancreas , pathology , syrian hamsters , animal model , latency stage , physiology , hamster
After a short latency (15 weeks), a 100% incidence of pancreatic neoplasms was induced in Syrian golden hamsters, following the administration of 2,2′‐dihydroxy‐di‐ n ‐propylnitrosamine (DHPN). Data extracted from reports of human pancreatic neoplasms were compared with findings relative to the induced neoplasms. The latter resembled human pancreatic tumors, in both biological and morphological aspects.