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Generalized melanosis complicating disseminated malignant melanoma in pregnancy: A case report
Author(s) -
Holcomb Barry W.,
Thigpen J. Tate,
Puckett James F.,
Morrison Francis S.
Publication year - 1975
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197505)35:5<1459::aid-cncr2820350534>3.0.co;2-9
Subject(s) - medicine , melanosis , melanoma , pregnancy , dermatology , complication , fetus , pathology , surgery , cancer research , genetics , biology
A case of generalized melanosis complicating disseminated malignant melanoma in pregnancy is described. Four features of this case, unique in combination, are discussed. First, generalized melanosis is a rare complication in macrophages of skin and other areas. Secondly, extensive bone lesions in the absence of roentgenographic changes are an uncommon occurrence. Thirdly, pregnancy probably has little effect on the course of melanoma, as illustrated by this case and a review of the literature. Finally, placental metastases may be more common than generally thought, yet may have little significance to the fetus.