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Malignant histiocytosis in a patient presenting with leukocytosis, eosinophilia, and lymph node granuloma
Author(s) -
Ballard James O.,
Binder Richard A.,
Rath Charles E.,
Powell Deborah
Publication year - 1975
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197505)35:5<1444::aid-cncr2820350531>3.0.co;2-y
Subject(s) - leukocytosis , medicine , eosinophilia , malignant histiocytosis , leukemoid reaction , pathology , lymph node , granuloma , histiocytosis , eosinophilic granuloma , malignancy , chemotherapy , histiocyte , immunology , disease
A patient with malignant histiocytosis presented with a number of unusual features including fever, leukemoid reaction, and eosinophilia. Other confusing findings included lymph node biopsies which showed reactive changes, noncaseating granuloma, and atypical Reed‐Sternberg cells. These features are compared with cases appearing in the literature. The course was rapidly progressive despite combination chemotherapy.