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Painful lytic bone lesion in an adult with chronic myelogenous leukemia
Author(s) -
Campbell Earl,
Maldonado Wilfred,
Suhrland George
Publication year - 1975
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197505)35:5<1354::aid-cncr2820350517>3.0.co;2-k
Subject(s) - chronic myelogenous leukemia , medicine , lytic cycle , osteolysis , lesion , leukemia , pathology , biopsy , bone marrow , immunology , radiology , virus
The occurrence of blast cell granulocytic tumors (chloromas, myeloblastomas) associated with chronic myelogenous leukemia has been well documented. However, the production of lytic lesions by nonmyeloblastomatous hematopoietic cell forms in chronic myelogenous leukemia has been described only once previously. The pain associated with osteolysis in this particular patient preceded roentgenographic appearance of lytic lesion and diagnosis of chronic myelogenous leukemia. Biopsy of lytic lesion demonstrated infiltration with cell forms nearly identical with those of simultaneously performed bone marrow aspiration.