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Anaplastic giant‐cell carcinoma of the thyroid. A study of treatment and prognosis
Author(s) -
Jereb B.,
Stjernswärd J.,
Löwhagen T.
Publication year - 1975
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197505)35:5<1293::aid-cncr2820350504>3.0.co;2-w
Subject(s) - medicine , anaplastic carcinoma , radiation therapy , carcinoma , surgery , thyroid , oncology
In 79 cases of histologically verified anaplastic giant‐cell carcinoma, symptoms, treatment, and prognosis were documented. Seventy‐eight patients are dead, the mean survival time being 2.5 months. One patient is cured. It was concluded that surgery and/or radiotherapy alone are not sufficient. The results from an additional 8 patients also treated with methotexate indicate a positive therapeutic effect, the mean survival time being 9.4 months. Disappearance of recurrent tumor or pulmonary metastases was noted in 2 patients.

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