Premium
Treatment of lymphoma
Author(s) -
Sullivan Margaret P.
Publication year - 1975
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197503)35:3+<991::aid-cncr2820350721>3.0.co;2-s
Subject(s) - lymphoma , medicine , histiocyte , diffuse large b cell lymphoma , large cell , pathology , burkitt's lymphoma , cancer , adenocarcinoma
Lymphomatous diseases (non‐Hodgkin's) of children differ markedly from those of adults in histology, natural history, and response to therapy. Information obtained from treating adults with lymphoma cannot be applied to children with equal success; the progress in treating children has been slow. The following types of non‐Hodgkin's lymphoma have been distinguished in children seen at the M. D. Anderson Hospital and Tumor Institute in the past 7 years: 1) diffuse undifferentiated lymphoma (Burkitt's lymphoma); 2) diffuse undifferentiated lymphoma (non‐Burkitt's lymphoma lacking leukemic propensity); 3) diffuse poorly differentiated lymphocytic lymphoma (non‐Burkitt's lymphoma with leukemic propensity (convoluted cell type); and 4) diffuse histiocytic lymphoma (histiocytic lymphoma). The interrelationships of age, sex, histology, and primary site are presented. The occurrence of mediastinal masses in non‐Burkitt's tumor (convoluted cell type) is particularly striking. Therapeutic regimens designed for specific types of non‐Hodgkin's lymphoma have improved the outcome of treatment in Burkitt's lymphoma, non‐Burkitt's lymphoma (convoluted cell type), and histiocytic lymphoma (Stages I and II) as compared with treatment regimens used prior to 1967.