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Salivary gland neoplasms following atomic radiation: Additional cases and reanalysis of combined data in a fixed population, 1957–1970
Author(s) -
Belsky Joseph L.,
Takeichi Nobuo,
Yamamoto Tsutomu,
Cihak Robert W.,
Hirose Fumio,
Ezaki Haruo,
Inoue Shozo,
Blot William J.
Publication year - 1975
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197502)35:2<555::aid-cncr2820350240>3.0.co;2-g
Subject(s) - medicine , salivary gland , population , pathology , radiation therapy , physiology , nuclear medicine , oncology , environmental health
A reappraisal was made of the relationship between exposure to atomic radiation in 1945 and the occurrence of salivary gland tumors in heavily exposed survivors. This was made possible by the discovery of 8 additional patients; the total now reported consists of 30 cases. In those exposed to 300+ rads, the number of cases was significantly (p < .01) greater than expected. This was found for the combined group and for malignant types, but not for histologically benign tumors. Our prior conclusion regarding the high‐dose radiation effect upon salivary gland neoplasia remains unchanged in the reanalysis; however, our suggestion that younger persons were at significantly greater risk is weakened.