Premium
Cell‐mediated immune reactions to tumor antigens with particular emphasis on immunity to human neoplasms
Author(s) -
Hellström Ingegerd,
Hellström Karl Erik
Publication year - 1974
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197410)34:8+<1461::aid-cncr2820340818>3.0.co;2-i
Subject(s) - medicine , immunity , immune system , cell mediated immunity , antigen , immunology , cellular immunity , emphasis (telecommunications) , electrical engineering , engineering
Findings on lymphocyte‐mediated destruction of animal and human tumor cells plated in vitro are reviewed. The role of blocking, “unblocking,” “potentiating,” and “arming” serum factors in tumor immunity is discussed. Evidence is presented from studies on human tumors that the in vitro measurement of lymphocyte‐mediated tumor cell killing and blocking serum activity (abrogating tumor cell killing by lymphocytes) shows a clinical correlation.