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Clustering of cases of Hodgkin's disease and leukemia
Author(s) -
Pike M. C.,
Smith P. G.
Publication year - 1974
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197410)34:8+<1390::aid-cncr2820340809>3.0.co;2-j
Subject(s) - medicine , cluster analysis , leukemia , disease , oncology , artificial intelligence , computer science
Time‐space “clusters” of leukemia cases have been reported since the 1930s; since 1960, a great number of such observations has been made. However, it is still an open question whether or not the phenomenon is real. 5 “Clustering” of Hodgkin's disease cases is a relatively new phenomenon. 6,17,18 The reports appear more convincing than those relating to leukemia, but closer analysis reveals possible serious methodological flaws which make their interpretation difficult. In this paper we consider the currently more interesting Hodgkin's disease situation, using the leukemia studies as a guide as to what pitfalls should be avoided. We then reverse the process and suggest cluster studies that should now be conducted in leukemia on the basis of what may be learned from the Hodgkin's disease studies.