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Lobular carcinoma in situ of the breast( Long‐term followup
Author(s) -
Wheeler James E.,
Enterline H. T.,
Roseman James M.,
Tomasulo Joseph P.,
McIlvaine Cheryl H.,
Fitts William T.,
Kirshenbaum James
Publication year - 1974
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197409)34:3<554::aid-cncr2820340313>3.0.co;2-7
Subject(s) - lobular carcinoma , medicine , biopsy , mastectomy , carcinoma , carcinoma in situ , breast cancer , breast carcinoma , radiology , mammary gland , ductal carcinoma , pathology , cancer
Ninety‐eight women with lobular carcinoma in situ (LICS) of the breast were identified over a 16‐year period. Consecutive slide review of all breast material over a 12‐year period identified 25 women with LCIS on biopsy who did not undergo mastectomy. Only 1 woman (4%) in a complete followup averaging 17.5 years developed ipsilateral invasive carcinoma. of 32 women with a contralateral breast at risk, 3 (9.7%) developed infiltrating carcinoma. LCIS was found with infiltrating carcinoma, especially of the lobular (small cell) type, with such frequency as to indicate a close relationship. However, the risk of subsequent development of infiltrating carcinoma in the breast with biopsyproven LCIS is shown to be substantially less than indicated by previous authors. This suggests that careful and prolonged followup may suffice for the woman whose breast biopsy contains lobular carcinoma in situ.