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Urine homovanillic acid and tissue dopa oxidase in patients with melanoma
Author(s) -
Morgan Lee Roy,
Lollev David,
Maddox Betty,
Samuels Monroe S.,
Krementz Edward T.
Publication year - 1974
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197406)33:6<1601::aid-cncr2820330619>3.0.co;2-n
Subject(s) - homovanillic acid , urine , medicine , melanoma , urinary system , oxidase test , cancer , enzyme , biochemistry , cancer research , chemistry , serotonin , receptor
The urinary content of homovanillic acid (HVA) and tumor dopa oxidase activities was studied in 169 patients with malignant melanoma. There was good agreement between the tumor dopa oxidase activity and urine HVA level in the same patient, considering the actual volume of tumor present is not taken into consideration. However, there was poor agreement in many instances when either urine HVA or tumor dopa oxidase alone was compared to the clinical condition. Cancer 33:1601–1606, 1974.