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The hazard of acute radiation pneumonitis in children receiving mediastinal radiation
Author(s) -
Littman Philip,
Davis Lawrence W.,
Nash Jerry,
Tefft Melvin,
Borns Patricia,
Lepanto Philip
Publication year - 1974
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197406)33:6<1520::aid-cncr2820330608>3.0.co;2-v
Subject(s) - medicine , mediastinum , thorax (insect anatomy) , pneumonitis , radiation therapy , radiology , concomitant , radiation pneumonitis , nuclear medicine , surgery , lung , anatomy
Two children are described who developed fatal pneumonitis after receiving what is considered to be an acceptable dose of irradiation to the whole thorax, plus additional radiotherapy to the mediastinum. The authors conclude that irradiation to the whole thorax with addition of further radiotherapy to the mediastinum is likely to cause severe acute radiation pneumonitis. The use of concomitant chemotherapy may accentuate the hazard. Cancer 33:1520–1525, 1974.