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Pseudosarcoma of the skin. An electron microscopic study and comparison with the fine structure of the spindle‐cell variant of squamous carcinoma
Author(s) -
Woyke S.,
Domagala W.,
Olszewski W.,
Korabiec M.
Publication year - 1974
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197404)33:4<970::aid-cncr2820330412>3.0.co;2-d
Subject(s) - histogenesis , ultrastructure , pathology , basal cell , spindle cell carcinoma , biology , anatomy , chemistry , medicine , immunohistochemistry
An ultrastructural study of a postirradiation pseudosarcoma of the skin is reported and compared to the spindle cell variant of squamous carcinoma in order to exclude epithelial histogenesis of the former. The pseudosarcoma tissue was composed of cells having the ultrastructural features characteristic of myofibroblasts. The cells of the spindle cell variant of the squamous carcinoma demonstrated the presence of tonofibrils which were joined by many desmosomes. These findings contradict the concept of an epithelial origin of the spindle‐shaped cells of pseudosarcoma.