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A clinicopathologic study of atypical lesions of the breast
Author(s) -
Ashikari Roy,
Huvos Andrew G.,
Snyder Ruth E.,
Lucas John C.,
Hutter Robert V. P.,
McDivitt Robert W.,
Schottenfeld David
Publication year - 1974
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197402)33:2<310::aid-cncr2820330203>3.0.co;2-c
Subject(s) - medicine , breast cancer , cancer , family history , mammography , mammary gland , pathology , radiology
Following the detection of non‐infiltrating cancer, there have been more extensive microscopic studies for various atypical lesions of the breast. At Memorial Hospital, 296 patients with these lesions were seen during the period 1960 to 1972. These lesions were found more often in middle aged women than is the case in average cancer patients, commonly seen in nulliparous women, in patients in whom breast cancer was found in the opposite breast, and in patients with a history of breast cancer in the family. The clinical and mammographic findings are quite similar to those in non‐infiltrating cancer. Occasionally, these lesions are quite difficult to distinguish from minimal breast cancer by histologic examination. In this study, the cumulative risk of breast cancer was approximately 4‐5% at 30 months and 9% at 48 months.