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Adenoid squamous cell carcinoma of the vulva
Author(s) -
Lasser Abraham,
Cornog John L.,
McL. Morris John
Publication year - 1974
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197401)33:1<224::aid-cncr2820330133>3.0.co;2-6
Subject(s) - vulva , adenoid , medicine , lichen sclerosus , pathology , basal cell , squamous carcinoma , dermatology , vulvar carcinoma , carcinoma , adenoid cystic carcinoma
Fifty cases of histologically proven invasive squamous cell carcinoma of the vulva were reviewed. It was found that 2 of the patients had extensive areas of adenoid squamous cell carcinoma, and 15 had focal changes. The adenoid variety of squamous cell carcinoma consists of rounded spaces, lined by squamous cells primarily of one cell thickness, and conatining in the lumen single or grouped dyskeratotic acantholytic cells. The incidence of lichen sclerosus et atrophicus in the 50 patients with squamous carcinoma of the vulva was found to be 18%. There was no statistical significance in the observed difference in mortality between patients with adenoid squamous and the usual variety of squamous cell carcinoma. Adenoid squamous carcinoma, which is often attributed to solar damage, has previously been described only in sun‐exposed areas of the skin. Our report is the first describing this entity in the vulva.