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Light microscopic identification of the ribosome‐lamella complex in “hairy cells” of leukemic reticuloendotheliosis
Author(s) -
Katayama Isao,
Nagy George K.,
Balogh Karoly
Publication year - 1973
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197310)32:4<843::aid-cncr2820320415>3.0.co;2-9
Subject(s) - lamella (surface anatomy) , cytoplasm , hairy cell leukemia , hairy cell , ribosome , electron microscope , cytoplasmic inclusion , pathology , biology , microbiology and biotechnology , medicine , leukemia , anatomy , rna , biochemistry , immunology , physics , optics , gene
Routine hematologic and histologic preparations revealed rod‐shaped structures in the cytoplasm of “hairy cells” in 3 of 11 patients with leukemic reticuloendotheliosis. These inclusions are identical with the ribosome‐lamella complex seen under the electron microscope in the hairy cells. The cytoplasmic inclusions can be of diagnostic value in the light microscopic differentiation of leukemic reticuloendotheliosis from other leukemias and lymphomas.