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Growth retardation in children after megavoltage irradiation of the spine
Author(s) -
Probert John C.,
Parker Bruce R.,
Kaplan Henry S.
Publication year - 1973
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197309)32:3<634::aid-cncr2820320316>3.0.co;2-a
Subject(s) - medicine , medulloblastoma , growth retardation , pediatrics , radiation therapy , lymphoblastic leukemia , sitting , irradiation , nuclear medicine , surgery , leukemia , pathology , pregnancy , physics , biology , nuclear physics , genetics
Twenty‐two children, under the age of 15, received complete spinal irradiation with a linear accelerator, for treatment of lymphoma, medulloblastoma, and acute lymphoblastic leukemia. Sixteen of the 22 children show retardation of growth of the spine. Ten children have a sitting height, which is a reflection of spinal length, more than two standard deviations from the normal mean for their age. Children receiving irradiation at the times of most active growth, under the age of 6 and at the time of puberty, show especially marked retardation of spinal growth.