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Origin of teratomas
Author(s) -
Ashley David J. B.
Publication year - 1973
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197308)32:2<390::aid-cncr2820320216>3.0.co;2-w
Subject(s) - blastula , medicine , teratoma , anatomy , pathology , embryo , biology , genetics , embryogenesis , gastrulation
The histologic, cytologic, and clinical features of teratomas are discussed in relation to the possible methods of origin of these unusual lesions. It is suggested that there are two groups of teratomas. One type seen in the gonads and possibly in the posterior abdominal wall is derived from germ cells by a process of parthenogenesis. The second type seen in the sacrococcygeal region, the head, and the chest is related to sequestration of cells of the blastula before differential blocking of the genome has occurred, and may be regarded as a derivative of an incomplete conjoined twin.