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Immunotherapy of malignant melanoma. A clinical trial
Author(s) -
McCarthy W. H.,
Cotton G.,
Carlon A.,
Milton G. W.,
Kossard S.
Publication year - 1973
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197307)32:1<97::aid-cncr2820320113>3.0.co;2-k
Subject(s) - medicine , melanoma , immunotherapy , malignant disease , gamma globulin , immunization , clinical trial , disease , oncology , active immunotherapy , immunology , cancer , antibody , cancer research
Fifty patients with metastatic malignant melanoma were treated with vaccines prepared by coupling goat serum gamma globulins to cells from their own tumors. With a minimum follow‐up of 18 months, it is believed that two patients showed definite objective remissions and four others had an unusual course of disease which might be a result of immunotherapy. Two other methods of active immunization with tumor cells were explored in small groups of patients, without evidence of success.