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Radiographic appearance of the chest following extended field radiation therapy for Hodgkin's disease. A consideration of time‐dose relationships
Author(s) -
Libshitz Herman I.,
Brosof Alan B.,
Southard Martha E.
Publication year - 1973
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197307)32:1<206::aid-cncr2820320131>3.0.co;2-9
Subject(s) - medicine , radiation therapy , pneumonitis , radiation pneumonitis , thorax (insect anatomy) , radiography , radiology , disease , radiation proctitis , pulmonary fibrosis , pericarditis , lung , surgery , proctitis , anatomy , ulcerative colitis
Radiation change in the thorax following extended field radiation therapy for Hodgkin's disease was reviewed retrospectively. All patients were treated with cobalt‐60. Strict criteria were established to exclude patients with previous radiation therapy, chemotherapy, evidence of pulmonary parenchymal disease, or inadequate radiogrophic follow‐up. Nineteen of 20 patients showed changes; 13 showed evidence of radiation pneumonitis. Nineteen showed evidence of radiation fibrosis or loss of volume. Radiation pneumonitis appeared more frequently at 8‐12 weeks following the completion of therapy. Radiation fibrosis was generally established by the ninth to twelth month following the completion of therapy. Two cases of radiation pericarditis were seen. There is a time‐dose relationship of the pulmonary parenchymal radiation changes that needs to be further defined.