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Sinus histiocytosis in non‐diagnostic scalene lymph node biopsies
Author(s) -
Silverberg Steven G.,
Frable William J.,
Brooks James W.
Publication year - 1973
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197307)32:1<177::aid-cncr2820320126>3.0.co;2-p
Subject(s) - medicine , lung cancer , lymph node , sinus (botany) , cancer , incidence (geometry) , lymph , pathology , radiology , botany , physics , optics , biology , genus
In view of the reported low incidence of sinus histiocytosis (SH) in benign diseases, an attempt was made to document whether the presence of SH in scalene lymph node biopsies was a reliable indicator of underlying cancer. Of 141 consecutive scalene node biopsies, 38 (27%) were diagnostic for various diseases and 3 were inadequate. The remaining 100 cases were analyzed for presence or absence of SH, and these findings were correlated with the presence or absence of clinically and pathologically documented cancer. SH was found not to be useful as an indicator of the presence of cancer, since only 26 of 41 SH‐positive cases were proven to have cancer. In lung cancer patients, the presence or absence of SH in scalene nodes did not provide useful prognostic information, since the rates of operability and of 1‐year survival were similar among SH‐positive and SH‐negative cases.