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Catecholamines in neuroblastoma cells from human bone marrow, tissue culture, and murine C‐1300 tumor
Author(s) -
Helson Lawrence,
Biedler June L.
Publication year - 1973
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197305)31:5<1087::aid-cncr2820310508>3.0.co;2-0
Subject(s) - bone marrow , neuroblastoma , human bone , pathology , medicine , intracellular , tissue culture , cell culture , staining , microbiology and biotechnology , cancer research , biology , in vitro , biochemistry , genetics
The formaldehyde‐induced fluorescence method for detection of intracellular catecholamines was applied to neuroblastoma cells in human bone marrow aspirates and cultured cells from human and murine sources. Based upon a conventional staining technique for bone marrow smears, fewer fluorescent cells than expected were detected. The production and storage of detectable amounts of catecholamines may vary with the growth phase of the cell.