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Hemangiopericytoma. An ultrastructural study
Author(s) -
Hahn Michael J.,
Dawson Richard,
Esterly James A.,
Joseph Donald J.
Publication year - 1973
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197301)31:1<255::aid-cncr2820310134>3.0.co;2-a
Subject(s) - hemangiopericytoma , ultrastructure , pericyte , pathology , cytoplasm , tumor cells , smooth muscle , mesenchymal stem cell , anatomy , cell , cell type , medicine , biology , microbiology and biotechnology , endothelial stem cell , cancer research , in vitro , biochemistry , genetics
An electron microscopic study was made of a nasal hemangiopericytoma. Previous ultrastructural studies of hemangiopericytomas established no uniform description of these tumor cells. The ultrastructure of this tumor revealed the presence of several cellular morphological variations. The majority of tumor cells resembled pericytes. Less frequently occurring tumor cells showed features compatible with smooth muscle cells, the cytoplasm being filled by bundles of fibrillar material and dense bodies. Numerous cells of transitional morphology between pericytes and smooth muscle cells were also present. The concept that pericytes are a transitional form from mesenchymal cell to smooth muscle cell is discussed.