Premium
Chemotherapy of ovarian cancer. New Approaches to Treatment
Author(s) -
Smith Julian P.,
Rutledge Felix,
Wharton J. Taylor
Publication year - 1972
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197212)30:6<1565::aid-cncr2820300623>3.0.co;2-h
Subject(s) - medicine , chemotherapy , cyclophosphamide , regimen , oncology , ovary , epithelial ovarian cancer , fluorouracil , ovarian cancer , surgery , drug , cancer , pharmacology
In an effort to develop a more effective treatment regimen for patients with advanced epithelial cancers of the ovary, patients treated with single agent chemotherapy with an alkylating agent; a three‐drug combination of actino‐mycin D, 5‐fluorouracil, and cyclophosphamide; chemotherapy followed by irradiation, and chemotherapy followed by surgery were compared. Only patients treated with chemotherapy followed by surgery had an improved survival over patients treated with a single alkylating agent.