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Diffuse eosinophilic granuloma of bone.A dramatic response to velban therapy>
Author(s) -
Kondi Edward S.,
Deckers Peter J.,
Gallitano Alphonse L.,
Khung Christian L.
Publication year - 1972
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197211)30:5<1169::aid-cncr2820300506>3.0.co;2-h
Subject(s) - eosinophilic granuloma , medicine , granuloma , infiltration (hvac) , pathology , eosinophilic , physics , thermodynamics
A patient with diffuse osseous infiltration by eosinophilic granuloma was treated with intravenous Velban once each week. Generalized bone pain rapidly diminished. Within 5 months, significant sclerosis and recalcification of all bony lesions was observed, and maintenance therapy with Velban has produced a prolonged, complete remission. This unusual response justifies consideration of this therapy in other patients with diffuse eosinophilic granuloma of bone and other related variants of the disease, histocytosis‐X.