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Papillomatosis of nasal cavity and paranasal sinuses (inverted papilloma, squamous papilloma). A clinicopathologic study
Author(s) -
Snyder Richard N.,
Perzin Karl H.
Publication year - 1972
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197209)30:3<668::aid-cncr2820300315>3.0.co;2-b
Subject(s) - papillomatosis , medicine , paranasal sinuses , papilloma , atypia , inverted papilloma , pathology , carcinoma , nasal cavity , dermatology , surgery
Papillomatosis is an uncommon benign tumor involving the mucous membranes of the nasal cavity and paranasal sinuses. It was approximately 1/25 as frequent as the ordinary nasal polyp. Thirty‐nine patients with this condition have been studied, including clinical and pathologic findings. Recurrences were common (documented 49%, with another 25% probable). Features associated with higher rates of recurrence were epithelial atypia, epithelial mucus droplets, and involvement of sinuses. Carcinoma was associated with papillomatosis, but the extent of this relationship depended on the criteria used. Invasive carcinoma arising in documented recurrent papillomatosis was uncommon (one patient, 3%). In three other cases (8%), relatively small foci of carcinoma were found within extensive papillomatosis. In another four lesions (10%), the specimen resected for a large invasive carcinoma also showed incidental foci of papillomatosis. In these, however, it was difficult to prove that the carcinoma had actually arisen within the papillomatous epithelium. Recommendations for treatment are made.