Premium
The gross rates of growth of human mammary carcinoma
Author(s) -
Kusama Satoru,
Spratt John S.,
Donegan William L.,
Watson Francis R.,
Cunningham Cynthia
Publication year - 1972
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197208)30:2<594::aid-cncr2820300241>3.0.co;2-2
Subject(s) - medicine , mammary carcinoma , carcinoma , cancer , mastectomy , breast cancer , metastasis , lymph node , breast carcinoma , gross examination , oncology , pathology
In a retrospective review of 912 patients with mammary cancer at the Ellis Fischel State Cancer Hospital (EFSCH), 199 patient records contained two or more gross measurements of a neoplastic focus in the breast, a lymph node, the lung, the chest wall, or other sites. The gross rates of growth were calculated from these measurements and correlated with the characteristics of the tumor and the hosts. The rates were independent of the anatomical site of the measured carcinoma, marital status, race, tumor size, frequency of lymph node metastasis at the time of mastectomy, and frequency and site of the postoperative metastasis. Doubling times did correlate directly with the age of the patients, duration of preoperative symptoms, and duration of survival after radical mastectomy. Tumor growth rate can account for some of the clinical characteristics of mammary carcinoma.