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Repression of propagation of ehrlich ascites tumors by means of attenuating tumor cells
Author(s) -
Maekawa Kazuyuki,
Kushibe Masahisa
Publication year - 1972
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197208)30:2<366::aid-cncr2820300210>3.0.co;2-b
Subject(s) - rna , ehrlich ascites , inoculation , moiety , medicine , ascites , cancer research , biochemistry , tumor cells , biology , chemistry , pathology , gene , stereochemistry
RNA obtained from Ehrlich ascites tumor cells, yeast, rice bran, and soy bean, and derivatives of RNA, as well as their complexes formed with some basic polymers, were examined to evaluate the effectiveness in inhibiting tumors. RNA complexes formed with a certain basic polymer were effective to some extent. By means of the pre‐inoculation of tumor cells properly treated with such an RNA complex, the incidence of the tumor was inhibited completely in the challenge inoculation. It could be concluded that the yeast RNA as well as the Ehr. RNA was as effective as the RNA moiety composing the complex.