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Occurrence of herpes‐ and adenovirus antibodies in patients with carcinoma of the cervix uteri.Measurement of antibodies to herpesvirus hominis (types 1 and 2), cytomegalovirus, EB‐virus, and adenovirus
Author(s) -
Vestergaard Bent Faber,
Hornsleth Allan,
Pedersen Søren Nødskov
Publication year - 1972
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197207)30:1<68::aid-cncr2820300111>3.0.co;2-0
Subject(s) - medicine , cytomegalovirus , herpesvirus hominis , antibody , herpes simplex virus , cervical cancer , cervix , virology , incidence (geometry) , virus , immunology , herpesviridae , cancer , viral disease , physics , optics
One hundred thirty‐five sera from patients with newly diagnosed, untreated cervical cancer and 115 sera from healthy women matched for age and socioeconomic background have been examined for antibodies to Herpesvirus hominis (types 1 and 2), cytomegalovirus, EB‐virus and adenovirus. Eighty‐five per cent of the patients with cervical cancer had antibodies to Herpesvirus hominis type 2 compared to 47% in the control group. The incidences of antibodies to cytomegalovirus and EB‐virus were significantly greater in the sera from patients with cervical cancer than in control sera. The incidence of antibodies to adenovirus was the same for both groups. The incidences of antibodies were not correlated to the clinical stages of the disease. In the control group, antibodies to Herpesvirus hominis type 2 and EB‐virus were found with higher incidence among women with low socioeconomic background than in women from higher social classes. Such a correlation was not seen in patients with cervical cancer.