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Intra‐arterial infusion—an adjuvant to the treatment of oral carcinoma
Author(s) -
Couture Jean,
Deschênes Luc
Publication year - 1972
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197206)29:6<1632::aid-cncr2820290630>3.0.co;2-s
Subject(s) - medicine , adjuvant , surgery , carcinoma , cancer , palliative care , nursing
Intra‐arterial infusion, since introduced to clinical use, has been used extensively as a palliative method in treating patients with oral cancer. However, from the studies reported, this approach to treatment offers limited palliation. The object of our study was to determine the value of primary infusion as an adjuvant to operation or irradiation. Results were reasonably good in a group of 39 patients treated by the method described. Tumor regressions of 75% or more were common in one group treated by infusion followed by conservative surgery; in one patient, complete tumor regression has persisted more than 7 years. After infusion, it was possible, in some older patients, to obtain excellent results without extensive radical surgical procedures. Although no firm conclusions can be drawn from this group of patients, the authors feel that, with proper case selection, some form of combined therapy might improve the treatment of carcinoma of the mouth. From these results, it is suggested that intra‐arterial infusion can be considered as part of the treatment of oral carcinoma, not only as a palliative measure, but also as an adjuvant to conventional methods.