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Detection of breast cancer by liquid crystal thermography. A preliminary report
Author(s) -
Davison Thomas W.,
Ewing Keith L.,
Fergason James,
Chapman Max,
Can Atila,
Voorhis C. C.
Publication year - 1972
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197205)29:5<1123::aid-cncr2820290502>3.0.co;2-8
Subject(s) - medicine , fibroadenoma , thermography , mammography , breast cancer , malignancy , cancer , gynecology , radiology , pathology , physics , infrared , optics
Liquid crystal (L.C.) thermographic study of 105 women with abnormal breast characteristics was undertaken to evaluate the efficiency of L.C. thermography in breast cancer detection. Six general thermographic signs were noted to occur in breasts affected by breast cancer. These signs were derived from L.C. thermograms of 17 patients with histologically proven carcinoma. Detection of palpable malignancies with L.C. thermography had a true‐positive rate of 82.3%. The false‐positive rate was 13.6%, and only one of 17 histologically proven malignancies gave no thermographic signs of malignancy. Liquid crystal thermograms of 197 apparently healthy women with no breast abnormalities were classified according to pattern type. Six distinct thermal pattern types were characterized with 3 subgroups distinguishable in each of 3 vascular pattern groups. The L.C. pattern type was studied as a function of age, past pregnancies, previous lactation, use or non‐use of oral contraceptives, and breast size. In general, women under 30 years of age, women with several past pregnancies, women who had lactated more than 10 months' total lifetime, women using oral contraceptives, and women with large breasts had a greater occurence of the vascular patterns. Women with abnormal breast characteristics (n = 100) and known lesions (fibrocystic disease, fibroadenoma, or carcinoma) were classified according to L.C. thermal pattern type. As expected, women with malignant lesions had a higher percentage of the vascular thermal pattern types.