Premium
Diagnostic cytology in urinary tract malignancy
Author(s) -
Prall Robert H.,
Wernett Carl,
Mims Mattlock M.
Publication year - 1972
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197204)29:4<1084::aid-cncr2820290458>3.0.co;2-n
Subject(s) - medicine , malignancy , cytology , urinary system , false positive rate , urine cytology , false negative reactions , medical diagnosis , radiology , pathology , statistics , cystoscopy , mathematics
Urinary cytology studies were performed on 306 patients from 1963 to 1969; 245 were suitable for critical review. Accurate diagnoses were made cytologically in 80% overall. Twenty‐three per cent of all negative reports were false, and 4% of all positive reports were false. Maintenance of strict criteria of malignancy is emphasized as a means of achieving a low false‐positive rate. Examination of multiple urine samples obtained by barbotage is suggested as a means for improving the false‐negative rate. Selected patients with both false‐positive and true‐positive cytologic findings are presented in detail, including those in whom malignancy was first demonstrated by cytologic means.