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Treatment of minor salivary gland malignancies of upper food and air passage epithelium. A review of 87 cases
Author(s) -
Kadish Sidney P.,
Goodman Max L.,
Wang C. C.
Publication year - 1972
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197204)29:4<1021::aid-cncr2820290450>3.0.co;2-p
Subject(s) - medicine , salivary gland , nasal cavity , paranasal sinuses , histopathology , radiation therapy , pathology , epithelium , oral cavity , adenocarcinoma , minor salivary glands , lymph node , cancer , surgery , dentistry
A review of 87 cases of adenocarcinoma of the epithelium of the upper food and air passages is presented. These are divided into 3 groups: nasal cavity and paranasal sinuses, oral cavity, and pharynges. Their clinical course and histopathology are described, and the results of treatment by surgery, radiation therapy, and a combination of the two are evaluated. The following conclusions are made: 1. minor salivary gland malignancies arising in the upper food and air passage epithelium are moderately radioresponsive and radiocurable; 2. their curability is a function of anatomic location and extent of lymph node metastases rather than histologic type; 3. failure of local control of these tumors is frequently manifested within 2 years, and 4. most published data regarding the radiotherapy of these minor salivary gland malignancies are based on outmoded kilovoltage techniques.