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Carcinoma of the uterine cervix, stages I and II, treated by radiation therapy and extensive surgery (1000 cases)
Author(s) -
Pilleron J. P.,
Durand J. C.,
Lenoble J. C.
Publication year - 1972
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197203)29:3<593::aid-cncr2820290310>3.0.co;2-w
Subject(s) - medicine , cervix , stage (stratigraphy) , radiation therapy , surgery , lymph node , uterine cervix , carcinoma , lymphadenectomy , radiology , cancer , paleontology , biology
More than 1,000 colpohysterectomies were performed at the Curie Foundation, between 1948 and 1968, with a low mortality rate (less than 1%) and a low urinary morbidity rate. Surgical intervention was preceded by uterovaginal curietherapy at 8000 mg/h. This technique resulted in total survival of 82% at Stage I and 60% at Stage II. It was found that when the cervix is not sterilized at the time of the intervention, performed 6 weeks after curietherapy, the nodes are more frequently invaded and the prognosis is lowered significantly. The percentage of node invasion was 11% at stage I and 20% at Stage II. Since 1966, lymphadenectomy has been extended to the primitive iliac nodes and is controlled on the lymphangiogram during the operation. Preoperative cobalt therapy is used in Stage I and Stage II with a swollen cervix. Surveillance by the radiotherapist and surgeon during the course of treatment is necessary in order to appreciate the reaction of the lesion to therapy and to assess the possibilities of an intervention.