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A new human cell line (FaDu) from a hypopharyngeal carcinoma
Author(s) -
Rangan S. R. S.
Publication year - 1972
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197201)29:1<117::aid-cncr2820290119>3.0.co;2-r
Subject(s) - cell culture , doubling time , ultrastructure , basal cell , cell , population , carcinoma cell , carcinoma , human cell , pathology , dna , line (geometry) , virology , biology , medicine , genetics , geometry , mathematics , environmental health
A human epithelial cell line, FaDu, from a squamous cell carcinoma of the hypopharynx has been isolated and established from a patient from Calcutta, India. The cell line has a population doubling time of approximately 50 hours. Ultrastructural observation reveals the presence of bundles of tonofilaments in the cells and desmosomal regions distributed at the boundaries of adjacent cells. The cell line is susceptible to infection by some RNA‐ and DNA‐containing viruses.